Search results for "clinical risk"

showing 10 items of 29 documents

Gene variants of osteoprotegerin, estrogen-, calcitonin- and vitamin D-receptor genes and serum markers of bone metabolism in patients with Gaucher d…

2018

Anca Zimmermann,1 Radu A Popp,2 Heidi Rossmann,3 Simona Bucerzan,4 Ioana Nascu,4 Daniel Leucuta,5 Matthias M Weber,1 Paula Grigorescu-Sido41Department of Endocrinology and Metabolic Diseases, 1st Clinic and Polyclinic of Internal Medicine, University of Mainz, Mainz, Germany; 2Department of Medical Genetics, University of Medicine and Pharmacy, Cluj-Napoca, Romania; 3Institute for Clinical Chemistry and Laboratory Medicine, University of Mainz, Mainz, Germany; 4Center of Genetic Diseases, 1st Pediatric Clinic, University of Medicine and Pharmacy, Cluj-Napoca, Romania; 5Department of Medical Informatics and Biostatistics, University of Medicine and Pharmacy, Cluj-Napoca, RomaniaPurpose: Oste…

0301 basic medicinemusculoskeletal diseasesmedicine.medical_specialtyTherapeutics and Clinical Risk ManagementOsteoporosisGaucher diseasegene variantsCalcitriol receptorBone remodeling03 medical and health sciencesOsteoprotegerinInternal medicineGenotypecalcitonin receptormedicinevitamin D receptorPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsCalcitonin receptorOriginal ResearchChemical Health and Safetybiologybusiness.industryGeneral Medicinemedicine.diseaseosteoporosis030104 developmental biologyEndocrinologyosteoprotegerinOsteocalcinbiology.proteinbusinessSafety ResearchEstrogen receptor alphaTherapeutics and Clinical Risk Management
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Introducing “healthcare resilience” in clinical risk management

2016

This paper reports the results of an explorative case study in an Italian hospital and presents a conceptual framework for healthcare resilience, which clarifies why and how healthcare structures need to be resilient in order to fully deal with clinical risk. In other words, it is not sufficient to take the “path to zero harm”. Healthcare companies have also to pursue strategies for maximizing the organizational resilience, in terms of resistance, reliability, redundancy and flexibility. This is quite important because, no matter which CRM technique and/or best practice is adopted, sometime adverse events occur. And, in this case, being resilient can help in dampening their negative consequ…

Clinical Risk Management Organizational ResilienceSettore ING-IND/35 - Ingegneria Economico-Gestionale
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The communication breakdown in the generation of the adverse event in an obstetrics and gynecology ward: a System Dynamics perspective.

2013

During the last two decades, the issue of clinical risk management became one of the key topics in the Health care sector due to the increasing attention to the patient safety and the increase in monetary and non monetary costs (insurance fees, image etc.). For this reason, in the healthcare sector have been imported risk management methods that have been successfully applied in other sector. However they are too static and linear to study such a complex and dynamic issue as the risk management. The objective of the research is to investigate, with a system dynamics perspective, the relationship between the communication and the adverse event in the Health Care, referring to the studies of …

Clinical risk management human factors System Dynamics
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Liability of clinical oncologists and the COVID-19 emergency: Between hopes and concerns

2020

Highlights • To contain COVID-19 spread, Italy is under a global lockdown except for health services and food supply. • In this scenario, growing apprehension concerning legal consequences is rising among health professionals. • Hospitals and health professionals are highly exposed to liability. • More articulated legal regulations are strongly needed.

Coronavirus disease 2019 (COVID-19)media_common.quotation_subjecteducationArticle03 medical and health sciencesPolitics0302 clinical medicineState (polity)clinical risk managementPandemicmedicine030212 general & internal medicineEthichealth care economics and organizationsHealthcare Professionalmedia_commonEthicsGovernmentCommunicable diseaseApprehensionbusiness.industrySARS-CoV-2Health PolicyLiabilityPublic relationshumanitiesOncology030220 oncology & carcinogenesismedicine.symptombusinessLegalJournal of Cancer Policy
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Evolution of risk management in health care system: Survey on the adverse events occurred in Palermo University Hospital Policlinico “Paolo Giaccone”

2019

Introduction. We aimed at carrying out a quantitative and qualitative analysis of claims for adverse events addressed to Palermo University Hospital Policlinico “Paolo Giaccone” in order to promote evidence-based interventions and increase patient safety. Methods. A retrospective study of 296 claims collected between 1st of January, 2014 and 31st of December, 2017 by Quality and Clinical Risk Management staff unit was performed along with descriptive analysis of any associated determinant factors. Results. The most frequent causes of claims consisted of wrong surgical procedures (33.8%), mistaken diagnoses (18.6%), falls (17.6%), infections (6.4%), postoperative complications (5.4%) and wro…

Hospitals UniversityAdverse eventEvidence-Based MedicineItalyMedical ErrorsRisk managementSurveys and QuestionnairesHumansPatient SafetyDelivery of Health CareQuality of Health CareRetrospective StudiesClinical risk
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Predictability of pharmaceutical spending in primary health services using Clinical Risk Groups

2014

Background: Risk adjustment instruments applied to existing electronic health records and administrative datasets may contribute to monitoring the correct prescribing of medicines. Objective: We aim to test the suitability of the model based on the CRG system and obtain specific adjusted weights for determined health states through a predictive model of pharmaceutical expenditure in primary health care. Methods: A database of 261,054 population in one health district of an Eastern region of Spain was used. The predictive power of two models was compared. The first model (ATC-model) used nine dummy variables: sex and 8 groups from 1 to 8 or more chronic conditions while in the second model (…

MaleECONOMIA APLICADAHealth StatusPopulationContext (language use)Pharmacy expenditureDrug CostsSex FactorsDrug TherapyDummy variablePrimary healthMedicineHumansPredictabilityeducationeducation.field_of_studyActuarial scienceModels StatisticalPrimary Health Carebusiness.industryHealth PolicyClinical Risk GroupsAge FactorsECONOMIA SOCIOLOGIA Y POLITICA AGRARIATest (assessment)Risk adjustmentOne HealthSpainChronic DiseasePredictive powerFemalebusinessWHO-ATC-Code
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A simplified clinical risk score predicts the need for early endoscopy in non-variceal upper gastrointestinal bleeding

2014

Abstract Background Pre-endoscopic triage of patients who require an early upper endoscopy can improve management of patients with non-variceal upper gastrointestinal bleeding. Aims To validate a new simplified clinical score (T-score) to assess the need of an early upper endoscopy in non variceal bleeding patients. Secondary outcomes were re-bleeding rate, 30-day bleeding-related mortality. Methods In this prospective, multicentre study patients with bleeding who underwent upper endoscopy were enrolled. The accuracy for high risk endoscopic stigmata of the T-score was compared with that of the Glasgow Blatchford risk score. Results Overall, 602 patients underwent early upper endoscopy, and…

MaleVariceal bleedingClinical scoremedicine.medical_treatmentSeverity of Illness IndexEndoscopy GastrointestinalHEMORRHAGERecurrenceRisk FactorsProspective StudiesAged 80 and overOUTCOMESFramingham Risk Scoremedicine.diagnostic_testIncidenceUpper endoscopyGastroenterologyMiddle AgedTIMESurvival RateItalyFemaleGastrointestinal HemorrhageClinical risk factormedicine.medical_specialtyRisk AssessmentDiagnosis DifferentialClinical score Endoscopy High endoscopic stigmata Upper gastrointestinal bleeding; GLASGOW-BLATCHFORD HEMORRHAGE TIME OUTCOMESmedicineHumansUpper gastrointestinal bleedingAgedHepatologybusiness.industryReproducibility of Resultsnon variceal upper gastrointestinal bleedingEndoscopymedicine.diseaseTriageGLASGOW-BLATCHFORDEndoscopySurgerySettore MED/18 - Chirurgia GeneraleEarly DiagnosisHigh endoscopic stigmataROC CurveTherapeutic endoscopyUpper gastrointestinal bleedingTriagebusinessFollow-Up StudiesDigestive and Liver Disease
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Cost of Type 2 Diabetes Patients with Chronic Kidney Disease Based on Real-World Data: An Observational Population-Based Study in Spain

2021

[EN] This study analyzed the prevalence, costs and economic impact of chronic kidney disease CKD in patients with T2D in a Spanish Health District using real-world data. Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia Clinico-La Malvarrosa Health District in the year 2015. Patients were stratified with the KDIGO classification for CKD. Additionally, patients were assigned to Clinical Risk Groups (CRGs) according to multimorbidity. Direct costs of primary and specialized care, and medication were estimated. The prevalence of T2D in the database population (n = 28,345) was 10.8% (mean age (SD) = 67.8 years …

Malehealthcare resourcesmedicine.medical_specialtyECONOMIA APLICADAHealth Toxicology and MutagenesisPopulationRenal functioncostsType 2 diabetesDiseaseArticleIndirect costsChronic kidney diseaseInternal medicineHealth caremedicineHumansRenal Insufficiency ChronicHealthcare resourcesBurden of careeducationAgededucation.field_of_studyDiabetisbusiness.industryClinical Risk GroupsPublic Health Environmental and Occupational HealthRType 2 diabetesHealth Care Costsmedicine.diseaseCostsKDIGO classificationCross-Sectional StudiesDiabetes Mellitus Type 2Spainburden of careInsuficiència renal crònicaMedicineFemaleObservational studyECONOMIA FINANCIERA Y CONTABILIDADtype 2 diabetesbusinesschronic kidney diseaseKidney diseaseInternational Journal of Environmental Research and Public Health
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Risk assessment in ginecology and obstetrics in Sicily: an approach based on Wolff's Criteria

2013

Objectives To apply Wolff’s Criteria to hospital discharge records (HDR) in order to detect adverse events worthy of further study. Methods Gynecology and Obstetrics Units of three Sicilian hospitals were considered and HDR regarding ordinary and day hospital admissions in 2008 were collected. A matched case-control study was designed, by random selection of 10 controls at maximum for each case. Matching was performed on the variables age and speciality of admission (gynecology or obstetrics). Results Out of a total of 7011 HDR examined, 114 cases were identified with Wolff’s Criteria. Multivariate analysis confirmed a statistically significant association with the origin of admission, diag…

Patient TransferReoperationGenital Neoplasms FemaleSettore MED/42 - Igiene Generale E ApplicataPatient ReadmissionRisk AssessmentSettore MED/01 - Statistica MedicaGynecologic Surgical ProceduresPregnancyRisk FactorsAmbulatory CarePrevalenceHumansHospital MortalityObstetrics and Gynecology Department HospitalRisk ManagementLength of StayDelivery ObstetricQuality ImprovementPatient DischargeIntensive Care UnitsItalyCase-Control StudiesWolff’s Criteria Adverse Events Clinical Risk Obstetrics GynecologyFemalePatient SafetyEmergencies
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Adult congenital heart disease: Special considerations for COVID-19 and vaccine allocation/prioritization

2021

Abstract Individuals with the highest risk for adverse outcomes of COVID-19 should be prioritized by the vaccine allocation policies. We have conducted a literature review of published studies, which comprehend congenital heart disease (CHD) and COVID-19, in order to present the overall evidences of both exposure and clinical risk of patients with adult congenital heart disease (ACHD) and to propose a risk profile schema for those patients to be incorporated into vaccine distribution decisions.

Prioritizationmedicine.medical_specialtyHeart diseaseCoronavirus disease 2019 (COVID-19)business.industryAdverse outcomesCOVID-19medicine.diseaseRisk profileArticleRisk factorsSchema (psychology)RC666-701ACHDMedicineDiseases of the circulatory (Cardiovascular) systembusinessIntensive care medicineClinical risk factorVaccine
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